模型信息
中文名称:MERS-CoV EMC/2012滴鼻感染新西兰白兔模型
英文名称:MERS-CoV EMC/2012 intransally infection of New Zealand white rabbit model
类型:MERS-CoV感染动物模型
分级:NA
用途:用于MERS-CoV感染研究。
研制单位:美国国家过敏和传染病研究所@@http://www.niaid.nih.gov/
保存单位:美国国家过敏和传染病研究所@@http://www.niaid.nih.gov/
研究背景
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制备方法
Male New Zealand white rabbits (Covance, Princeton, NJ) between five to nine months of age were anesthetized with a combination of intramuscular dexmedetomidine and isoflurane inhalation. Animals were inoculated intranasally (i.n.) with virus diluted in 1ml of MERS-CoV in Leibovitz-15 (L15) media (GIBCO), or mock-infected with 1ml of media alone. Rabbits following infection with either 103 or 105 TCID50 of EMC/2012 strain. n = 3 rabbits per group.
评价验证
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生物安全性
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讨论与结论
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了解中析
实验室仪器
合作客户
